The place for ACE inhibitors

The place of ACE inhibitors in the current treatment of chronic heart failure.

In assessing the place of any therapy for chronic heart failure (CHF) there are two main considerations does the treatment make patients feel better and does it make them live longer? It is then important to see whether this treatment offers any advantages over other treatments; here the side effect profile may be a crucial determinant. There is now sufficient evidence to compare angiotensin co...

ACE, ACE inhibitors, and other JNK.

The renin-angiotensin system (RAS) plays a pivotal role in the regulation of blood pressure, volume homeostasis, vascular function, and cell growth. In what is considered the classic RAS, renin is released from juxtaglomerular cells of the kidney into the circulation where it converts angiotensinogen from the liver to angiotensin I. Angiotensin I is subsequently hydrolyzed by a peptidyl dipepti...

ACE inhibitors and anaesthesia.

During the last decade, two angiotensin converting enzyme (ACE) inhibitors, captopril and enalapril, have become accepted into clinical practice and are regarded as effective treatments for hypertension and congestive cardiac failure.' A third agent, lisinopril, had recently become available and others are likely to be introduced in the near future. It is clear, therefore, that more patients, w...

Ace Inhibitors: a Comprehensive Review

Hypertension is a chronic increase in blood pressure, characterized as primary and secondary hypertension. The disorder is associated with various risk factors like obesity, diabetes, age, lack of exercise etc. Hypertension is being treated since ancient times by Ayurvedic, Chinese and Unani medicine. Now various allopathic drugs are available which include diuretics, calcium channel blockers, ...

eComment: Statins and ACE-inhibitors.